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Oxidative stress arises from an imbalance between reactive oxygen species (ROS) and cellular antioxidant defenses, contributing to DNA damage, protein misfolding, and cellular aging

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For the plucked group, the drug was administered every day, and the skin of the backs of the mice was taken and embedded or preserved at −80°C on the third day and the sixth day after the plucking of the hairs for qRT-PCR or western blot