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Central administration demonstrated early feasibility: intracerebroventricular (icv) or intrathecal delivery robustly increased wakefulness and locomotion in rodents [49,50], but invasiveness, instability, and potential desensitization restrict clinical translation [51,52] https://i.ebayimg.com/images/g/4RcAAOSwtVZm00Eb/s-l1200.png Frontiers | Metabolic mediators: microbial-derived metabolites as key regulators of anti-tumor immunity, immunotherapy, and chemotherapy uncategorized-family Flavor:Duo Pack (Mixed Berry + Lemonade)

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